Cephalexin

[dobermom]

Is cephalexin safe in pregnant dogs?

[mara]

In humans it is safe to use during pregnancy. Small amounts are secreted through breast milk.

I'll try and find some canine info now.....
Can't seem to find anything about canines and keflex....sorry..

[Dauxside]

Teresa here's what I found -

http://www.dogflu.ca/cephalexin
at the bottom it says not to use but no reason.

http://www.springerlink.com/content/ru803064h9652w67/
scientific blurb says no problems in lab rats

http://www.veterinarypartner.com/Con...C=31&A=538&S=0
this report says it crosses the placenta but not milk and is prefered not to be used in prenant animal.

[weezyNollie]

According the Plumb's Veterinary Drug Handbook:

Reproductive/Nursing Safety
Cephalosporins have been shown to cross the placenta and safe use of them during pregnancy have not been firmly established, but neither have there been any documented teratogenic problems associated with these drugs. However, use only when the potential benefits outweigh the risks. In humans, the FDA categorizes this drug as category B for use during pregnancy (Animal studies have not yet demonstrated risk to the fetus, but there are no adequate studies in pregnant women; or animal studies have shown an adverse effect, but adequate studies in pregnant women have not demonstrated a risk to the fetus in the first trimester of pregnancy, and there is no evidence of risk in later trimesters.)